Optical Features

• AgileOptix Spinning Disk: Uses dual microlens-enhanced spinning disk technology to provide a flat field of view and deep tissue penetration. 

• 7-Laser Illumination: Outfitted with 7 solid-state lasers spanning 405 nm to 730 nm, cutting acquisition times significantly compared to traditional LED arrays.

• 8 Imaging Channels: Supports high-plex assays utilizing dyes like DAPI, CFP, FITC, YFP, TRITC, TexasRed, Cy5, and Cy7. 

• Automated Water Immersion: Implements custom Nikon water immersion objectives that boost signal intensity up to 4x while drastically reducing aberrations in deep tissue.

Software Capabilities

• MetaXpress Acquire: Powers automated, high-throughput workflows across multi-well formats up to 1536-well plates. 

• QuickID Targeted Acquisition: Pre-scans plates at a low magnification to target rare cellular events or regions, automatically zooming in for high-resolution imaging. 

• IN Carta Analysis: Uses machine learning/deep learning algorithms to segment complex 3D structures and handle phenotypic classifications effortlessly

Experimental Flexibility

• Multi-Modality: Capable of switching between widefield fluorescence, confocal imaging, brightfield, and phase contrast modes.

• Environmental Control: Regulates temperature, CO₂, and humidity to sustain multi-day, live-cell kinetic assays